Inhibitory Effect of Gliclazide on Platelet Adhesiveness and Aggregation in Alloxan Diabetic Rabbits

Hypoglycemic and antioxidant effect of oleuropein in alloxan-diabetic rabbits.

Patients with diabetes mellitus are likely to develop certain complication such as retinopathy, nephropathy and neuropathy as a result of oxidative stress and overwhelming free radicals. Treatment of diabetic patients with antioxidant may be of advantage in attenuating these complications. Oleuropein, the active constituent of olive leaf (Olea europaea), has been endowed with many beneficial an...

Hypoglycemic effect of Biophytum sensitivum in the alloxan diabetic rabbits.

Hypoglycaemic effect of a Neapalese plant Biophytum sensitivum was investigated in the alloxan diabetic male rabbits of different severities: subdiabetic (Alloxan recovered; AR), mild diabetic (MD) and severely diabetic (SD). Assessment of activity of the extract, prepared from the plant leaves, was done by fall in fasting plasma glucose (FPG) and improvement in the oral glucose tolerance test ...

Effect of α-lipoic acid on gliclazide-induced hypoglycemia/antihyperglycemia in normal/alloxan-induced diabetic rats

Inhibitory Effect of Propolis on Platelet Aggregation In Vitro

Platelet hyperactivity plays an important role in arterial thrombosis and atherosclerosis. The present study was aimed to investigate the effects of different extracts of propolis and components of flavonoids on platelet aggregation. Platelet-rich plasma was prepared and incubated in vitro with different concentrations of the tested extracts and components of flavonoids. Platelets aggregation w...

Platelet adhesiveness: the effect of centrifugation on the measurement of adhesiveness in platelet-rich plasma.

Platelet adhesiveness has been measured in citrated whole blood and in platelet-rich plasma obtained from normal subjects, splenectomized patients, and from patients in whom the diagnosis of recurrent venous thrombosis had been made. The duration of centrifugation used in the preparation of platelet-rich plasma was found to have a profound effect on the measurement of platelet adhesiveness beca...